Impact of the post-treatment conditions of parent silica on the silanization of n-octadecyl bonded silica packings in reversed-phase high-performance liquid chromatography

被引：14

作者：

Grossmann, F ^{[1
]}

Ehwald, V ^{[1
]}

von Hohenesche, CD ^{[1
]}

Unger, KK ^{[1
]}

机构：

[1] Univ Mainz, Inst Anorgan Chem & Analyt Chem, D-55128 Mainz, Germany

来源：

JOURNAL OF CHROMATOGRAPHY A | 2001年 / 910卷 / 02期

关键词：

stationary phases; LC; post-treatment procedures; silanization; silica; n-octadecyl bonded; calcination; rehydroxylation;

D O I：

10.1016/S0021-9673(00)01194-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Native mesoporous silica beads were subjected to a sequence of post-treatment procedure including hydrochloric acid treatment, calcination and subsequent rehydroxylation. The post-treated silica beads were converted into RP-18 silica by silanization with monochloro- and dimethoxy-n-octadecylsilanes, respectively. The influence of post-treatments and silanization conditions on the physico-chemical characteristics and on the chromatographic behaviour of the RP-silicas was studied. Also the changes of the pore structural parameters and the silanol group densities during the post-treatment and silanization were assessed. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：223 / 236

页数：14

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