The role of laminin in embryonic cell polarization and tissue organization

被引：232

作者：

Li, SH

Edgar, D

Fässler, R

Wadsworth, W

Yurchenco, PD ^{[1
]}

机构：

[1] Robert Wood Johnson Med Sch, Dept Pathol & Lab Med, Piscataway, NJ 08854 USA

[2] Univ Liverpool, Dept Human Anat & Cell Biol, Liverpool L69 3G3E, Merseyside, England

[3] Max Planck Inst Biochem, Dept Mol Med, D-82152 Martinsried, Germany

来源：

DEVELOPMENTAL CELL | 2003年 / 4卷 / 05期

关键词：

D O I：

10.1016/S1534-5807(03)00128-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Genetic analyses have revealed that members of the laminin glycoprotein family are required for basement membrane assembly and cell polarization, with subsequent effects on cell survival and tissue organization during metazoan embryogenesis. These functions depend upon the cooperation between laminin polymerization and cell anchorage mediated via interactions with beta1-integrins, dystroglycan, and other cell surface receptors.

引用

收藏

页码：613 / 624

页数：12

相关论文

共 99 条

[1] Analysis of heparin, α-dystroglycan and sulfatide binding to the G domain of the laminin α1 chain by site-directed mutagenesis [J].

Andac, Z ;

Sasaki, T ;

Mann, K ;

Brancaccio, A ;

Deutzmann, R ;

Timpl, R .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 287 (02) :253-264

[2]

Aumailley M, 2000, J CELL SCI, V113, P259

[3] Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants [J].

Baum, PD ;

Garriga, G .

NEURON, 1997, 19 (01) :51-62

[4] Integrins in development:: Moving on, responding to, and sticking to the extracellular matrix [J].

Bökel, C ;

Brown, NH .

DEVELOPMENTAL CELL, 2002, 3 (03) :311-321

[5] Skin and hair follicle integrity is crucially dependent on β1 integrin expression on keratinocytes [J].

Brakebusch, C ;

Grose, R ;

Quondamatteo, F ;

Ramirez, A ;

Jorcano, JL ;

Pirro, A ;

Svensson, M ;

Herken, R ;

Sasaki, T ;

Timpl, R ;

Werner, S ;

Fässler, R .

EMBO JOURNAL, 2000, 19 (15) :3990-4003

[6] Integrins in invasive growth [J].

Brakebusch, C ;

Bouvard, D ;

Stanchi, F ;

Saki, T ;

Fässler, R .

JOURNAL OF CLINICAL INVESTIGATION, 2002, 109 (08) :999-1006

[7]

Byrd N, 2002, DEVELOPMENT, V129, P361

[8] Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation [J].

Chen, Y ;

Li, XF ;

Eswarakumar, VP ;

Seger, R ;

Lonai, P .

ONCOGENE, 2000, 19 (33) :3750-3756

[9] Self-assembly of laminin isoforms [J].

Cheng, YS ;

Champliaud, MF ;

Burgeson, RE ;

Marinkovich, MP ;

Yurchenco, PD .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) :31525-31532

[10]

Colognato H, 2000, DEV DYNAM, V218, P213, DOI 10.1002/(SICI)1097-0177(200006)218:2<213::AID-DVDY1>3.0.CO

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