The effect of lithium iodide on the acid-promoted cyclization of 4-[(1-indolylcarbonyl)methyl]-1,4-dihydropyridines

被引：8

作者：

Bennasar, ML

Jimenez, JM

Sufi, BA

Bosch, J

机构：

[1] Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 42期

关键词：

D O I：

10.1016/0040-4039(96)01703-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,4-Dihydropyridines 3 resulting from the addition of the enolate derived from 1-acetylindole (1) to pyridinium salts 2 do not undergo cyclization under the usual acidic conditions, but do satisfactorily cyclize to the tetracyclic derivatives 4 by treatment with TsOH in the presence of lithium iodide. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：7653 / 7656

页数：4

共 14 条

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