Primary pulmonary hypertension, Castleman's disease and human herpesvirus-8

被引：37

作者：

Bull, TM

Cool, CD

Serls, AE

Rai, PR

Parr, J

Neid, JM

Geraci, MW

Campbell, TB

Voelkel, NF

Badesch, DB

机构：

[1] Univ Colorado, Sch Med, Div Pulm Sci & Crit Care Med, Dept Med,Pulm Hypertens Ctr, Denver, CO 80262 USA

[2] Univ Colorado, Hlth Sci Ctr, Dept Pathol, Denver, CO 80262 USA

[3] Univ Colorado, Hlth Sci Ctr, Div Infect Dis, Denver, CO 80262 USA

来源：

EUROPEAN RESPIRATORY JOURNAL | 2003年 / 22卷 / 03期

关键词：

endothelial cell; human herpesvirus-8; plexiform lesion; primary pulmonary hypertension;

D O I：

10.1183/09031936.03.00006903

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Primary pulmonary hypertension (PPH) and Castleman's disease (CD) are rare conditions infrequently encountered in clinical practice. In this paper, two patients diagnosed with both of these diseases are reported. The authors speculate that rather than being a chance occurrence, these conditions are linked by a common angio-proliferative mechanism. Therefore, an association between infection with the human herpesvirus-8 and the diseases of PPH and CD was sought. Evidence of human herpesvirus-8 infection was found in the lung tissue and, specifically, in the plexiform lesions from one of the patients.

引用

收藏

页码：403 / 407

页数：5

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