Asymmetric allylation. An effective strategy for the convergent synthesis of highly functionalized homoallylic alcohols

被引：35

作者：

Williams, DR ^{[1
]}

Brooks, DA ^{[1
]}

Meyer, KG ^{[1
]}

Clark, MP ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 40期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0040-4039(98)01557-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A survey of stereoselective syntheses of highly-functionalized homoallylic alcohols is described via asymmetric allylation. initial transmetalation from an allylic stannane to a C-2 symmetric chiral borane controller is followed by low temperature addition to aldehydes efficiently effecting convergent strategies to complex targets. (C) 1998 Elsevier Science Ltd. All rights reserved.

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收藏

页码：7251 / 7254

页数：4

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