Biomaterials integrated with electronic elements: en route to bioelectronics

被引:177
作者
Willner, I [1 ]
Willner, B [1 ]
机构
[1] Hebrew Univ Jerusalem, Inst Chem, IL-91904 Jerusalem, Israel
关键词
D O I
10.1016/S0167-7799(01)01634-1
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Bioelectronics is a progressing interdisciplinary research field that involves the integration of biomaterials with electronic transducers, such as electrodes, field-effect-transistors or piezoelectric crystals. Surface engineering of biomaterials, such as enzymes, antigen-antibodies or DNA on the electronic supports, controls the electrical properties of the biomaterial-transducer interface and enables the electronic transduction of biorecognition events, or biocatalyzed transformation, on the transducers, Bioelectronic sensing devices, biosensors of tailored sensitivities and specificities, are being developed.
引用
收藏
页码:222 / 230
页数:9
相关论文
共 90 条
[1]   COORDINATION CHEMISTRY IN 2 DIMENSIONS - CHEMICALLY MODIFIED ELECTRODES [J].
ABRUNA, HD .
COORDINATION CHEMISTRY REVIEWS, 1988, 86 :135-189
[2]  
ALBERY WJ, 1981, ANNU REP PROG CHEM C, V78, P377
[3]   Molecular recognition of artificial single-electron acceptor cosubstrates by glucose oxidase? [J].
Alzari, P ;
Anicet, N ;
Bourdillon, C ;
Moiroux, J ;
Saveant, JM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (28) :6788-6789
[4]   INTRAMOLECULAR ELECTRON-TRANSFER RATES IN FERROCENE-DERIVATIZED GLUCOSE-OXIDASE [J].
BADIA, A ;
CARLINI, R ;
FERNANDEZ, A ;
BATTAGLINI, F ;
MIKKELSEN, SR ;
ENGLISH, AM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (16) :7053-7060
[5]   Sensing and amplification of oligonucleotide-DNA interactions by means of impedance spectroscopy: a route to a Tay-Sachs sensor [J].
Bardea, A ;
Patolsky, F ;
Dagan, A ;
Willner, I .
CHEMICAL COMMUNICATIONS, 1999, (01) :21-22
[6]   Amplified microgravimetric quartz crystal-microbalance analyses of oligonucleotide complexes: a route to a Tay-Sachs biosensor device [J].
Bardea, A ;
Dagan, A ;
Ben-Dov, I ;
Amit, B ;
Willner, I .
CHEMICAL COMMUNICATIONS, 1998, (07) :839-840
[7]  
Bardea A, 2000, ELECTROANAL, V12, P1097, DOI 10.1002/1521-4109(200010)12:14<1097::AID-ELAN1097>3.3.CO
[8]  
2-O
[9]   NAD(+)-dependent enzyme electrodes: Electrical contact of cofactor-dependent enzymes and electrodes [J].
Bardea, A ;
Katz, E ;
Buckmann, AF ;
Willner, I .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (39) :9114-9119
[10]   Piezoelectric immunosensors for urine specimens of Chlamydia trachomatis employing quartz crystal microbalance microgravimetric analyses [J].
BenDov, I ;
Willner, I ;
Zisman, E .
ANALYTICAL CHEMISTRY, 1997, 69 (17) :3506-3512