Ketoester methacrylate resin, secondary amine clean-up in the presence of primary amines

被引：10

作者：

Yu, ZR

Alesso, S

Pears, D

Worthington, PA

Luke, RWA

Bradley, M

机构：

[1] Avecia, Manchester M9 8ZS, Lancs, England

[2] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

[3] Syngenta, Jealotts Hill Res Stn, Bracknell RG42 6EY, Berks, England

[4] AstraZeneca, Macclesfield SK10 4TG, Cheshire, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 16期

关键词：

D O I：

10.1039/b101395p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A ketoester resin was developed as the basis for a selective scavenger for primary amines in the presence of secondary amines. The utility of the scavenger was demonstrated with a range of reductive amination chemistries with both mono- and diamines. The resin's specificity is based on the removal of the primary amines via their enamines.

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页码：1947 / 1952

页数：6

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