DNA cleavage by photogenerated Rh2(O2CCH3)4(H2O)2+

被引：54

作者：

Fu, PKL ^{[1
]}

Bradley, PM ^{[1
]}

Turro, C ^{[1
]}

机构：

[1] Ohio State Univ, Dept Chem, Columbus, OH 43210 USA

来源：

INORGANIC CHEMISTRY | 2001年 / 40卷 / 11期

关键词：

D O I：

10.1021/ic010118w

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Irradiation of Rh-2(O2CCH3)(4)(H2O)(2) with visible light in the presence of electron accepters results in the formation of the oxidized complex, Rh-2(O2CCH3)(4)- (H2O)(2)(+). Photogenerated Rh-2(O2CCH3)(4)(H2O)(2)(+) is able to cleave plasmid DNA, whereas the Rh-2(O2CCH3)(4)(L)(2)(+) complexes with nonlabile axial ligands, L, such as py (pyridine) and PPh3 (triphenylphosphine), do not cleave the double helix. Rh-2(O2CCH3)(4)(H2O)(2)(+) [GRAPHICS]

引用

页码：2476 / +

页数：3

共 25 条

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