The architectural organization and mechanistic function of group II intron structural elements

被引：124

作者：

Qin, PZ

Pyle, AM

机构：

[1] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY 10032 USA

[2] Columbia Univ, Dept Appl Phys, Howard Hughes Med Inst, New York, NY 10032 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(98)80062-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Group II introns are large, self-splicing RNAs and mobile genetic elements that provide good model systems for studies of RNA folding. The structures and mechanistic functions of individual domains are being elucidated, and long-range tertiary interactions between the domains are being identified, thus helping to define the three-dimensional architecture of the intron.

引用

页码：301 / 308

页数：8

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