Demyelinating disease and hepatitis B vaccination - Is there a link?

被引:15
作者
Jefferson, T
Heijbel, H
机构
[1] Hlth Reviews Ltd, Mytchett GU16 6JP, Surrey, England
[2] Cochrane Vaccines Field, UK Cockrane Ctr, Oxford, England
[3] Swedish Inst Infect Dis Control, Lund, Sweden
关键词
D O I
10.2165/00002018-200124040-00002
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The recent decision by the French government to compensate 3 recipients of hepatitis B vaccine preceding the onset of multiple sclerosis presumes a possible causal link and brings into question the use of current rules of causality assessment. Available evidence does not support a causal link or is equivocal but the accuracy of current methods of vaccine surveillance should be urgently improved. Larger and longer randomised trials, updated summaries of evidence, linked databases, prospective vaccination registers, bar-coding of vaccines and standardisation of adverse event definitions are possible measures to address current problems.
引用
收藏
页码:249 / 254
页数:6
相关论文
共 22 条
[21]  
Usonis V, 1999, ACTA MED LITUANICA, P187
[22]   No increase in demyelinating diseases after hepatitis B vaccination [J].
Zipp, F ;
Weil, JG ;
Einhäupl, KM .
NATURE MEDICINE, 1999, 5 (09) :964-965