An ICT-based strategy to a colorimetric and ratiometric fluorescence probe for hydrogen sulfide in living cells

被引：353

作者：

Yu, Fabiao ^{[2
]}

Li, Peng ^{[1
]}

Song, Ping ^{[1
]}

Wang, Bingshuai ^{[1
]}

Zhao, Jianzhang ^{[2
]}

Han, Keli ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Beijing 100864, Peoples R China

[2] Dalian Univ Technol, Sch Chem Engn, Dalian 116024, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 23期

关键词：

H2S; ROLES; RAT; NEUROMODULATOR; HYPERTENSION; PATHOGENESIS; REDUCTION; PERFUSION; GAS;

D O I：

10.1039/c2cc17658k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present a colorimetric and ratiometric fluorescent probe Cy-N-3 that exhibits a selective response to H2S. The probe employs a near-infrared cyanine as a fluorophore, and is equipped with an operating azide unit. It is readily employed for assessing intracellular H2S levels, and confocal ratiometric imaging is achieved successfully.

引用

页码：2852 / 2854

页数：3

共 52 条

[1] A CRITICAL-REVIEW OF THE LITERATURE ON HYDROGEN-SULFIDE TOXICITY [J].

BEAUCHAMP, RO ;

BUS, JS ;

POPP, JA ;

BOREIKO, CJ ;

ANDJELKOVICH, DA .

CRC CRITICAL REVIEWS IN TOXICOLOGY, 1984, 13 (01) :25-97

[2] Measurement of reduced sulphur compounds contained in aqueous matrices by direct injection into a gas chromatograph with a flame photometric detector [J].

Bérubé, PR ;

Parkinson, PD ;

Hall, ER .

JOURNAL OF CHROMATOGRAPHY A, 1999, 830 (02) :485-489

[3] Hydrogen sulfide and erectile function: a novel therapeutic target [J].

Bianca, Roberta d'Emmanuele di Villa ;

Sorrentino, Raffaella ;

Mirone, Vincenzo ;

Cirino, Giuseppe .

NATURE REVIEWS UROLOGY, 2011, 8 (05) :286-289

[4] Sulfide-selective chemosignaling by a Cu2+ complex of dipicolylamine appended fluorescein [J].

Choi, Myung Gil ;

Cha, Sunyoung ;

Lee, Haekyung ;

Jeon, Hye Lim ;

Chang, Suk-Kyu .

CHEMICAL COMMUNICATIONS, 2009, (47) :7390-7392

[5] Signaling recognition events with fluorescent sensors and switches [J].

de Silva, AP ;

Gunaratne, HQN ;

Gunnlaugsson, T ;

Huxley, AJM ;

McCoy, CP ;

Rademacher, JT ;

Rice, TE .

CHEMICAL REVIEWS, 1997, 97 (05) :1515-1566

[6] New roles for cysteine and transsulfuration enzymes:: Production of H2S, a neuromodulator and smooth muscle relaxant [J].

Dominy, JE ;

Stipanuk, MH .

NUTRITION REVIEWS, 2004, 62 (09) :348-353

[7] RETRACTED: Brain hydrogen sulfide is severely decreased in Alzheimer's disease (Retracted Article) [J].

Eto, K ;

Asada, T ;

Arima, K ;

Makifuchi, T ;

Kimura, H .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 293 (05) :1485-1488

[8] Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs [J].

Fiorucci, S ;

Antonelli, E ;

Distrutti, E ;

Rizzo, G ;

Mencarelli, A ;

Orlandi, S ;

Zanardo, R ;

Renga, B ;

Di Sante, M ;

Morelli, A ;

Cirino, G ;

Wallace, JL .

GASTROENTEROLOGY, 2005, 129 (04) :1210-1224

[9] The third gas:: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis [J].

Fiorucci, S ;

Antonelli, E ;

Mencarelli, A ;

Orlandi, S ;

Renga, B ;

Rizzo, G ;

Distrutti, E ;

Shah, V ;

Morelli, A .

HEPATOLOGY, 2005, 42 (03) :539-548

[10] The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver [J].

Fiorucci, Stefano ;

Distrutti, Eleonora ;

Cirino, Giuseppe ;

Wallace, John L. .

GASTROENTEROLOGY, 2006, 131 (01) :259-271

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