Production of a hypoglycemic, extracellular polysaccharide from the submerged culture of the mushroom, Phellinus linteus

被引：102

作者：

Kim, DH ^{[1
]}

Yang, BK ^{[1
]}

Jeong, SC ^{[1
]}

Park, JB ^{[1
]}

Cho, SP ^{[1
]}

Das, S ^{[1
]}

Yun, JW ^{[1
]}

Song, CH ^{[1
]}

机构：

[1] Taegu Univ, Dept Biotechnol, Kyungsan 712714, Kyungbuk, South Korea

来源：

BIOTECHNOLOGY LETTERS | 2001年 / 23卷 / 07期

关键词：

extracellular polysaccharide; hypoglycemic effect; mushroom; Phellinus linteus; submerged mycelial culture;

D O I：

10.1023/A:1010312513878

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Mycelial growth and extracellular polysaccharide production of Phellinus linteus were optimal at pH 5 and 25 degreesC. Maximum biomass production (14.2 g l(-1)) was after 15 d of cultivation, whereas, extracellular polysaccharide was maximal (3.5 g l(-1)) after 21 d. The hypoglycemic effect of the polysaccharide, investigated in streptozotocin-induced diabetic rats, decreased plasma glucose, total cholesterol and triacylglycerol concentrations by 49%, 32%, and 28%, respectively, and aspartate aminotransferase activity by 20%. The results indicate the potential of this polysaccharide to prevent hyperglycemia in diabetic patients.

引用

页码：513 / 517

页数：5

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