The PROSITE database, its status in 1999

被引:920
作者
Hofmann, K
Bucher, P [1 ]
Falquet, L
Bairoch, A
机构
[1] Swiss Inst Expt Canc Res, Swiss Inst Bioinformat, CH-1066 Epalinges, Switzerland
[2] Stoffel GmbH, MEMOREC, D-50829 Cologne, Germany
[3] Univ Geneva, Dept Med Biochem, Swiss Inst Bioinformat, CH-1211 Geneva 4, Switzerland
关键词
D O I
10.1093/nar/27.1.215
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The PROSITE database (http://www.expasy.ch/sprot/ prosite.html) consists of biologically significant patterns and profiles formulated in such a way that with appropriate computational tools it can help to determine to which known family of protein (if any) a new sequence belongs, or which known domain(s) it contains.
引用
收藏
页码:215 / 219
页数:5
相关论文
共 16 条
  • [1] [Anonymous], COMPUTATIONAL MOL BI
  • [2] A NEW-GENERATION OF INFORMATION-RETRIEVAL TOOLS FOR BIOLOGISTS - THE EXAMPLE OF THE EXPASY WWW SERVER
    APPEL, RD
    BAIROCH, A
    HOCHSTRASSER, DF
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (06) : 258 - 260
  • [3] The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1998
    Bairoch, A
    Apweiler, R
    [J]. NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 38 - 42
  • [4] BAIROCH A, 1994, NUCLEIC ACIDS RES, V22, P3583
  • [5] The PROSITE database, its status in 1997
    Bairoch, A
    Bucher, P
    Hofmann, K
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (01) : 217 - 221
  • [6] A flexible motif search technique based on generalized profiles
    Bucher, P
    Karplus, K
    Moeri, N
    Hofmann, K
    [J]. COMPUTERS & CHEMISTRY, 1996, 20 (01): : 3 - 23
  • [7] BUCHER P, 1994, ISMB 94, P53
  • [8] Doolittle R.F., 1986, Of Urfs and Orfs: A Primer on How to Analyze Derived Amino Acid Sequences
  • [9] Hidden Markov models
    Eddy, SR
    [J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 1996, 6 (03) : 361 - 365
  • [10] PROFILE ANALYSIS - DETECTION OF DISTANTLY RELATED PROTEINS
    GRIBSKOV, M
    MCLACHLAN, AD
    EISENBERG, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (13) : 4355 - 4358