Cystine mimetics - solid phase lanthionine synthesis

被引：24

作者：

Matteucci, M

Bhalay, G

Bradley, M ^{[1
]}

机构：

[1] Univ Southampton, Dept Chem, Combinatorial Ctr Excellence, Southampton SO17 1BJ, Hants, England

[2] Novartis Pharmaceut, Horsham RH12 5AB, W Sussex, England

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 07期

基金：

英国工程与自然科学研究理事会;

关键词：

solid phase synthesis; lanthionine; dehydro peptides; lantibiotics;

D O I：

10.1016/j.tetlet.2003.12.074

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total solid phase synthesis of an analogue of the B ring of nisin was achieved, in a biomimetic fashion, via the solid phase diastereoselective cyclisation of a dehydrothiol-containing peptide. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：1399 / 1401

页数：3

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