Truncated xpt gene present in invasive Streptococcus pneumoniae may have implications for MLST schemes

被引：5

作者：

Diggle, MA

Clarke, SC

机构：

[1] Stobhill Gen Hosp, Scottish Meningococcus & Pneumococcus Reference, Glasgow G21 3UW, Lanark, Scotland

[2] Univ Glasgow, Div Infect & Immun, Inst Biomed & Life Sci, Glasgow G12 8QQ, Lanark, Scotland

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2005年 / 54卷 / 10期

基金：

英国惠康基金;

关键词：

D O I：

10.1099/jmm.0.46106-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A serotype 1 disease-causing pneumococcus possessing a truncated xanthine phosphoribosyltransferase (xpt) housekeeping gene is described. The deletion is within the gene region used for multi-locus sequence typing (MLST) and may have occurred through genetic transformation or capsule switch between clones. The identification of this deletion in a clinical isolate therefore warrants highlighting due to potential errors that may ensue in isolate characterization and due to the fact that deletions may occur in other genes in this or other species characterized by MLST.

引用

收藏

页码：909 / 912

页数：4

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