diastereoselectivity;
enones;
Michael additions;
magnesium;
silicon;
D O I:
10.1055/s-2003-41467
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
In the presence of MgCl2, dimethylsilyl (DMS) enolates 1 smoothly reacted with alpha-enones in DMF to form 1,5-diketones 3 in moderate to high yields. The Michael addition proceeded with moderate to high anti-diastereoselectivity.