High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III):: in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts

被引：67

作者：

Yang, VXD ^{[1
]}

Gordon, ML

Tang, SJ

Marcon, NE

Gardiner, G

Qi, B

Bisland, S

Seng-Yue, E

Lo, S

Pekar, J

Wilson, BC

Vitkin, IA

机构：

[1] Univ Toronto, Dept Med Biophys, Toronto, ON M5G 2M9, Canada

[2] St Michaels Hosp, Ctr Therapeut Endoscopy & Endoscop Oncol, Toronto, ON M5B 1W8, Canada

[3] St Michaels Hosp, Dept Pathol, Toronto, ON M5B 1W8, Canada

[4] Univ Toronto, Dept Radiat Oncol, Toronto, ON M5G 2M9, Canada

[5] Univ Hlth Network, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada

[6] Photon Res Ontario, Biophoton Facil, Toronto, ON M5G 2M9, Canada

来源：

OPTICS EXPRESS | 2003年 / 11卷 / 19期

关键词：

D O I：

10.1364/OE.11.002416

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We previously described a fiber based Doppler optical coherence tomography system [1] capable of imaging embryo cardiac blood flow at 4 similar to 16 frames per second with wide velocity dynamic range [2]. Coupling this system to a linear scanning fiber optical catheter design that minimizes friction and vibrations, we report here the initial results of in vivo endoscopic Doppler optical coherence tomography (EDOCT) imaging in normal rat and human esophagus. Microvascular flow in blood vessels less than 100 mum diameter was detected using a combination of color-Doppler and velocity variance imaging modes, during clinical endoscopy using a mobile EDOCT system. (C) 2003 Optical Society of America.

引用

页码：2416 / 2424

页数：9

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