Transglutaminases in vascular biology: Relevance for vascular remodeling and atherosclerosis

被引：73

作者：

Bakker, Erik N. T. P. ^{[1
]}

Pistea, Adrian ^{[1
]}

VanBavel, Ed ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Med Phys, NL-1100 DE Amsterdam, Netherlands

来源：

JOURNAL OF VASCULAR RESEARCH | 2008年 / 45卷 / 04期

关键词：

transglutaminase; factor XIII; vascular remodeling; atherosclerosis;

D O I：

10.1159/000113599

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The transglutaminase (Tgase) family consists of nine known members of whom at least three are expressed in the vascular system: type 1 Tgase, type 2 Tgase and factor XIII. The cross-linking of proteins is a characteristic feature of Tgases, of well-known importance for stabilizing the blood clot and providing mechanical strength to tissues. However, recent data suggest that Tgases play a role in several other processes in vascular biology. These newly discovered areas include endothelial barrier function, small artery remodeling, and atherosclerosis. Copyright (C) 2008 S. Karger AG, Basel.

引用

页码：271 / 278

页数：8

共 75 条

[31]

Heilmann L, 2004, CLIN HEMORHEOL MICRO, V31, P49

[32] IDENTIFICATION OF INTRACELLULAR FACTOR-XIII IN HUMAN-MONOCYTES AND MACROPHAGES [J].

HENRIKSSON, P ;

BECKER, S ;

LYNCH, G ;

MCDONAGH, J .

JOURNAL OF CLINICAL INVESTIGATION, 1985, 76 (02) :528-534

[33] Correlation between vasoconstrictor roles and mRNA expression of α1-adrenoceptor subtypes in blood vessels of genetically engineered mice [J].

Hosoda, C ;

Tanoue, A ;

Shibano, M ;

Tanaka, Y ;

Hiroyama, M ;

Koshimizu, T ;

Cotecchia, S ;

Kitamura, T ;

Tsujimoto, G ;

Koike, K .

BRITISH JOURNAL OF PHARMACOLOGY, 2005, 146 (03) :456-466

[34]

Jones RA, 1997, J CELL SCI, V110, P2461

[35] Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine [J].

Karpuj, MV ;

Becher, MW ;

Springer, JE ;

Chabas, D ;

Youssef, S ;

Pedotti, R ;

Mitchell, D ;

Steinman, L .

NATURE MEDICINE, 2002, 8 (02) :143-149

[36]

Kielty CM, 2002, J CELL SCI, V115, P2817

[37] Flow-dependent remodeling of small arteries - The stimuli and the sensors are (still) in question [J].

Koller, Akos .

CIRCULATION RESEARCH, 2006, 99 (01) :6-9

[38] Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages [J].

Koseki-Kuno, S ;

Yamakawa, M ;

Dickneite, G ;

Ichinose, A .

BLOOD, 2003, 102 (13) :4410-4412

[39]

KROGSTAD DJ, 1991, BLOOD CELLS, V17, P229

[40] Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase [J].

Lai, TS ;

Hausladen, A ;

Slaughter, TF ;

Eu, JP ;

Stamler, JS ;

Greenberg, CS .

BIOCHEMISTRY, 2001, 40 (16) :4904-4910

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