Enzyme-mediated protecting group chemistry on the hydroxyl groups of nucleosides

被引：33

作者：

Prasad, AK ^{[1
]}

Wengel, J ^{[1
]}

机构：

[1] ODENSE UNIV,DEPT CHEM,DK-5230 ODENSE M,DENMARK

来源：

NUCLEOSIDES & NUCLEOTIDES | 1996年 / 15卷 / 7-8期

关键词：

D O I：

10.1080/07328319608002435

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Enzymes are well known catalysts for carrying out regio- and stereoselective reactions in organic synthesis. Results from enzyme-mediated protections and deprotections of the hydroxyl groups of pentofuranose nucleosides are discussed in this review.

引用

页码：1347 / 1359

页数：13

共 38 条

[1] PRODRUGS OF 9-(BETA-D-ARABINOFURANOSYL)ADENINE .2. SYNTHESIS AND EVALUATION OF A NUMBER OF 2',3'-DI-O-ACYL DERIVATIVES AND 3',5'-DI-O-ACYL DERIVATIVES
BAKER, DC
HASKELL, TH
PUTT, SR
SLOAN, BJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (03) : 273 - 279
[2] FACILE ACCESS TO 2'-O-ACYL PRODRUGS OF 1-(BETA-D-ARABINOFURANOSYL)-5(E)-(2-BROMOVINYL)URACIL (BVARAU) VIA REGIOSELECTIVE ESTERASE-CATALYZED HYDROLYSIS OF 2',3',5'-TRIESTERS
BARALDI, PG
BAZZANINI, R
MANFREDINI, S
SIMONI, D
ROBINS, MJ
[J]. TETRAHEDRON LETTERS, 1993, 34 (19) : 3177 - 3180
[3] DAMKJAER DL, 1994, NUCLEOS NUCLEOT, V13, P1801
[4] HIV INHIBITORS TARGETED AT THE REVERSE-TRANSCRIPTASE
DECLERCQ, E
[J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1992, 8 (02) : 119 - 137
[5] ANTISENSE OLIGONUCLEOTIDES
DEMESMAEKER, A
HANER, R
MARTIN, P
MOSER, HE
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (09) : 366 - 374
[6] PHENYLACETYL GROUP AS ENZYME-CLEAVABLE AMINOPROTECTION OF PURINE NUCLEOSIDES
DINEVA, MA
GALUNSKY, B
KASCHE, V
PETKOV, DD
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (12) : 2781 - 2784
[7] DRUECKHAMMER DG, 1991, SYNTHESIS-STUTTGART, P499
[8] DUEHOLM KL, 1992, SYNTHESIS-STUTTGART, P1
[9] GOTOR V, 1992, SYNTHESIS-STUTTGART, P626
[10] GRACIAALLES LF, 1993, TETRAHEDRON LETT, V34, P6337

← 1 2 3 4 →