Modelling the disposable soma theory of ageing

被引:53
作者
Drenos, F [1 ]
Kirkwood, TBL [1 ]
机构
[1] Univ Newcastle, Inst Ageing & Hlth, Sch Clin Med Sci Gerontol, Henry Wellcome Lab Biogerontol Res, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1016/j.mad.2004.09.026
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
We describe a mathematical model. developed using the Mathematica programming system of the disposable soma theory of ageing. The model makes explicit predictions about the optimal strategies for investment in somatic maintenance versus investments in growth and reproduction and confirms the central prediction of the disposable soma theory that the optimum investment in somatic maintenance is less than what would be required for indefinite longevity. We also describe how the optimal investment in maintenance is affected by varying the parameters that specify the schedules of reproduction and mortality. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:99 / 103
页数:5
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