Ni-Catalyzed Reduction of Inert C-O Bonds: A New Strategy for Using Aryl Ethers as Easily Removable Directing Groups

被引：218

作者：

Alvarez-Bercedo, Paula ^{[1
]}

Martin, Ruben ^{[1
]}

机构：

[1] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 49期

关键词：

CROSS-COUPLING REACTIONS; CARBON-OXYGEN; ACTIVATION; CLEAVAGE; CONSTRUCTION; AMINATION; REAGENTS; METALS; ESTERS;

D O I：

10.1021/ja106943q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.

引用

页码：17352 / 17353

页数：2

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