Ultrahigh-resolution optical coherence tomography with a fiber laser source at 1 μm

被引:73
作者
Lim, H [1 ]
Jiang, Y
Wang, YM
Huang, YC
Chen, ZP
Wise, FW
机构
[1] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92612 USA
[2] Univ Calif Irvine, Dept Biomed Engn, Irvine, CA 92612 USA
[3] Cornell Univ, Dept Appl Phys, Ithaca, NY 14853 USA
关键词
D O I
10.1364/OL.30.001171
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report a compact, high-power, fiber-based source for ultrahigh-resolution optical coherence tomography (OCT) near 1 mu m. The practical source is based on a short-pulse, ytterbium-doped fiber laser and on generation of a continuum spectrum in a photonic crystal fiber. The broadband emission has an average power of 140 mW and offers an axial resolution of 2.1 mu m in air (< 1.6 mu m in biological tissue). The generation of a broad bandwidth is robust and efficient. We demonstrate ultrahigh-resolution, time-domain OCT imaging of in vitro and in vivo biological tissues. (c) 2005 Optical Society of America.
引用
收藏
页码:1171 / 1173
页数:3
相关论文
共 14 条
[1]  
*AM NATL STAND I, 1993, SAFE US LAS
[2]   Compact, broad-bandwidth fiber laser for sub-2-μm axial resolution optical coherence tomography in the 1300-nm wavelength region [J].
Bizheva, K ;
Povazay, B ;
Hermann, B ;
Sattmann, H ;
Drexler, W ;
Mei, M ;
Holzwarth, R ;
Hoelzenbein, T ;
Wacheck, V ;
Pehamberger, H .
OPTICS LETTERS, 2003, 28 (09) :707-709
[3]   Ultrahigh resolution real time OCT imaging using a compact femtosecond Nd:Glass laser and nonlinear fiber [J].
Bourquin, S ;
Aguirre, AD ;
Hartl, I ;
Hsiung, P ;
Ko, TH ;
Fujimoto, JG ;
Birks, TA ;
Wadsworth, WJ ;
Bünting, U ;
Kopf, D .
OPTICS EXPRESS, 2003, 11 (24) :3290-3297
[4]   Ultrahigh-resolution optical coherence tomography [J].
Drexler, W .
JOURNAL OF BIOMEDICAL OPTICS, 2004, 9 (01) :47-74
[5]   Coherence properties of supercontinuum spectra generated in photonic crystal and tapered optical fibers [J].
Dudley, JM ;
Coen, S .
OPTICS LETTERS, 2002, 27 (13) :1180-1182
[6]   Ultrahigh-resolution optical coherence tomography using continuum generation in an air-silica microstructure optical fiber [J].
Hartl, I ;
Li, XD ;
Chudoba, C ;
Ghanta, RK ;
Ko, TH ;
Fujimoto, JG ;
Ranka, JK ;
Windeler, RS .
OPTICS LETTERS, 2001, 26 (09) :608-610
[7]   Optical coherence tomography using a continuous-wave, high-power, Raman continuum light source [J].
Hsiung, PL ;
Chen, Y ;
Ko, TH ;
Fujimoto, JG ;
de Matos, CJS ;
Popov, SV ;
Taylor, JR ;
Gapontsev, VP .
OPTICS EXPRESS, 2004, 12 (22) :5287-5295
[8]   OPTICAL COHERENCE TOMOGRAPHY [J].
HUANG, D ;
SWANSON, EA ;
LIN, CP ;
SCHUMAN, JS ;
STINSON, WG ;
CHANG, W ;
HEE, MR ;
FLOTTE, T ;
GREGORY, K ;
PULIAFITO, CA ;
FUJIMOTO, JG .
SCIENCE, 1991, 254 (5035) :1178-1181
[9]  
Ilday FÖ, 2003, OPT LETT, V28, P1362, DOI 10.1364/OL.28.001362
[10]   Generation of 2-nJ pulses from a femtosecond ytterbium fiber laser [J].
Lim, H ;
Ilday, FÖ ;
Wise, FW .
OPTICS LETTERS, 2003, 28 (08) :660-662