Chromosome capture: Take me to your kinetochore

被引：4

作者：

Odde, DJ ^{[1
]}

机构：

[1] Univ Minnesota, Dept Biomed Engn, Minneapolis, MN 55455 USA

来源：

CURRENT BIOLOGY | 2005年 / 15卷 / 09期

关键词：

D O I：

10.1016/j.cub.2005.04.027

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

To form a proper mitotic spindle, all kinetochores must capture at least one microtubule plus end. A new computational modeling study shows that a search-and-capture mechanism based on spatially unbiased microtubule dynamic instability is too slow to account for the experimentally observed rate of chromosome capture.

引用

页码：R328 / R330

页数：3

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