A case of Aspergillus mediastinitis after heart transplantation successfully treated with liposomal amphotericin B, caspofungin and voriconazole

被引：31

作者：

Forestier, E

Remy, V

Lesens, O

Martinot, M

Hansman, Y

Eisenmann, B

Christmann, D

机构：

[1] Hop Univ Strasbourg, Dept Infect Dis, F-67094 Strasbourg, France

[2] Hop Louis Pasteur, Dept Internal Med, F-68000 Colmar, France

[3] Hop Univ Strasbourg, Vasc & Cardiac Surg Dept, F-67094 Strasbourg, France

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2005年 / 24卷 / 05期

关键词：

D O I：

10.1007/s10096-005-1327-5

中图分类号：

R51 [传染病];

学科分类号：

100401 [流行病与卫生统计学];

摘要：

Reported here is a case of mediastinitis caused by Aspergillus fumigatus and Staphylococcus epidermidis following a heart transplantation that was successfully treated with amphotericin B in combination with new antifungal drugs (caspofungin and voriconazole), antibiotics and superficial wound drainage. A review of the literature revealed that Aspergillus as a cause of mediastinitis has been rarely described. In the few existing reports, evolution was generally fatal, especially in immunocompromised patients, despite treatment with antifungal drugs and surgery.

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页码：347 / 349

页数：3

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