Human enteric viruses in Coquina clams associated with a large hepatitis A outbreak

被引：48

作者：

Bosch, A ^{[1
]}

Sánchez, G

Le Guyader, F

Vanaclocha, H

Haugarreau, L

Pintó, RM

机构：

[1] Univ Barcelona, Dept Microbiol, E-08028 Barcelona, Spain

[2] IFREMER, Dept Microbiol, F-44311 Nantes 03, France

[3] Generalitat Valenciana, Dept Epidemiol, Valencia 46010, Spain

来源：

WATER SCIENCE AND TECHNOLOGY | 2001年 / 43卷 / 12期

关键词：

hepatitis; shellfish; PCR; genotyping;

D O I：

10.2166/wst.2001.0712

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

An outbreak of hepatitis A, affecting 183 people, occurred in Valencia (Spain). Epidemiological evidence pointed to an association of the outbreak with consumption of Coquina clams (Donax sp), imported frozen from Peru. Shellfish were analysed for the presence of hepatitis A virus (HAV), enteroviruses, rotaviruses, astroviruses, caliciviruses and hepatitis E virus. HAV was detected in 75% of assayed shellfish samples. Other enteric viruses were occasionally found in the same samples. Molecular epidemiological analysis of fragments of the VP1 /2A and the 5 ' end of the genome from shellfish and sera isolates, revealed the presence of six variants belonging to a single genotype.

引用

页码：61 / 65

页数：5

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