学术探索
学术期刊
新闻热点
数据分析
智能评审

The membrane-proximal external region of HIV-1 gp41: a vaccine target worth exploring

被引：79
作者：
Zwick, MB [1 ]
机构：
[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA
来源：
AIDS | 2005年 / 19卷 / 16期
关键词：
HIV gp41; neutralizing antibodies; vaccine design; membrane proximal region; fusion inhibitors;
D O I：
10.1097/01.aids.0000189850.83322.41
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：1725 / 1737
页数：13
相关论文
共 150 条
  • [1] Cytokine, chemokine, and costimulatory molecule modulation to enhance efficacy of HIV vaccines
    Ahlers, JD
    Belyakov, IM
    Berzofsky, JA
    [J]. CURRENT MOLECULAR MEDICINE, 2003, 3 (03) : 285 - 301
  • [2] Ait-Azzouzene D, 2004, IMMUNOL REV, V200, P272
  • [3] Tolerance-induced receptor selection:: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection
    Aït-Azzouzene, D
    Skog, P
    Retter, M
    Kouskoff, V
    Hertz, M
    Lang, J
    Kench, J
    Chumley, M
    Melamed, D
    Sudaria, J
    Gavin, A
    Martensson, A
    Verkoczy, L
    Duong, B
    Vela, J
    Nemazee, D
    [J]. IMMUNOLOGICAL REVIEWS, 2004, 197 : 219 - 230
  • [4] HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide
    Alfsen, A
    Bomsel, M
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (28) : 25649 - 25659
  • [5] ARNOLD GF, 2004, AIDS VACCINE
  • [6] Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
    Baba, TW
    Liska, V
    Hofmann-Lehmann, R
    Vlasak, J
    Xu, WD
    Ayehunie, S
    Cavacini, LA
    Posner, MR
    Katinger, H
    Stiegler, G
    Bernacky, BJ
    Rizvi, TA
    Schmidt, R
    Hill, LR
    Keeling, ME
    Lu, YC
    Wright, JE
    Chou, TC
    Ruprecht, RM
    [J]. NATURE MEDICINE, 2000, 6 (02) : 200 - 206
  • [7] Structural basis for paramyxovirus-mediated membrane fusion
    Baker, KA
    Dutch, RE
    Lamb, RA
    Jardetzky, TS
    [J]. MOLECULAR CELL, 1999, 3 (03) : 309 - 319
  • [8] MOLECULAR PROFILE OF AN ANTIBODY-RESPONSE TO HIV-1 AS PROBED BY COMBINATORIAL LIBRARIES
    BARBAS, CF
    COLLET, TA
    AMBERG, W
    ROBEN, P
    BINLEY, JM
    HOEKSTRA, D
    CABABA, D
    JONES, TM
    WILLIAMSON, RA
    PILKINGTON, GR
    HAIGWOOD, NL
    CABEZAS, E
    SATTERTHWAIT, AC
    SANZ, I
    BURTON, DR
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1993, 230 (03) : 812 - 823
  • [9] Structural analysis of the epitope of the Anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion
    Barbato, G
    Bianchi, E
    Ingallinella, P
    Hurni, WH
    Miller, MD
    Cilibertol, G
    Cortese, R
    Bazzo, R
    Shiver, JW
    Pessi, A
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2003, 330 (05) : 1101 - 1115
  • [10] The mechanism and regulation of chromosomal V(D)J recombination
    Bassing, CH
    Swat, W
    Alt, FW
    [J]. CELL, 2002, 109 : S45 - S55
12345678910