Alzheimer's disease as a disconnection syndrome?

被引：565

作者：

Delbeuck, X

Van der Linden, M

Collette, F

机构：

[1] Univ Geneva, Cognit Psychopathol Unit, Fac Psychol & Sci Educ, CH-1205 Geneva, Switzerland

[2] Univ Liege, Neuropsychol Dept, Liege, Belgium

来源：

NEUROPSYCHOLOGY REVIEW | 2003年 / 13卷 / 02期

关键词：

Alzheimer's disease; disconnection; neuropsychology;

D O I：

10.1023/A:1023832305702

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

This paper reviews the growing amount of evidence supporting the hypothesis that Alzheimer's disease includes a disconnection syndrome. This evidence came mainly from neuropathological, electrophysiological, and neuroimaging studies. Moreover, a few recent neuropsychological studies have also explored the effects of a disconnection between cerebral areas on cognitive functioning. Finally, and more generally, the contribution of this interpretation to the understanding of Alzheimer's disease cognitive deficits is considered.

引用

页码：79 / 92

页数：14

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