Effect of pravastatin on cerebral infarcts and white matter lesions

被引：101

作者：

ten Dam, VH

van den Heuvel, DMJ

van Buchem, MA

Westendorp, RGJ

Bollen, ELEM

Ford, I

de Craen, AJM

Blauw, GJ

机构：

[1] Leiden Univ, Dept Gen Internal Med, NL-2300 RA Leiden, Netherlands

[2] Leiden Univ, Dept Radiol, NL-2300 RA Leiden, Netherlands

[3] Leiden Univ, Dept Neurol, NL-2300 RA Leiden, Netherlands

[4] N Glasgow Univ NHS Trust, Robertson Ctr Biostat, Glasgow, Lanark, Scotland

来源：

NEUROLOGY | 2005年 / 64卷 / 10期

关键词：

D O I：

10.1212/01.WNL.0000161844.00797.73

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors examined the effect of pravastatin 40 mg daily on the progression of ischemic brain lesions using repeated brain MRI. After a mean treatment period of 33 months, there was an increase in total ischemic lesion load of 1.1 cm(3) (p < 0.001) in the 270 placebo-treated subjects and 1.1 cm(3) (p < 0.001) in the 265 pravastatin-treated subjects. There was no difference between the two treatment groups (p = 0.73).

引用

页码：1807 / 1809

页数：3

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