Different progression rates for deep white matter hyperintensities in elderly men and women

被引：99

作者：

van den Heuvel, DMJ

Admiraal-Behloul, F

ten Dam, VH

Olofsen, H

Bollen, ELEM

Murray, HM

Blauw, GJ

Westendorp, RGJ

de Craen, AJM

van Buchem, MA

机构：

[1] Leiden Univ, Med Ctr, Dept Radiol, NL-2300 RC Leiden, Netherlands

[2] Leiden Univ, Med Ctr, Div Image Proc, NL-2300 RC Leiden, Netherlands

[3] Leiden Univ, Med Ctr, Dept Gerontol & Geriatr, NL-2300 RC Leiden, Netherlands

[4] Leiden Univ, Med Ctr, Gen Internal Med Sect, NL-2300 RC Leiden, Netherlands

[5] Leiden Univ, Med Ctr, Dept Neurol, NL-2300 RC Leiden, Netherlands

[6] Univ Glasgow, Robertson Ctr Biostat, Glasgow G12 8QQ, Lanark, Scotland

来源：

NEUROLOGY | 2004年 / 63卷 / 09期

关键词：

D O I：

10.1212/01.WNL.0000143058.40388.44

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors investigated the progression of white matter hyperintensities (WMHs) in a large population of elderly men and women. After 3 years of follow-up, women had accumulated approximately twice as much deep WMH (DWMH) as men. The progression of periventricular WMH was the same for men and women. Gender differences may affect the pathogenesis of DWMH, which in turn may result in different clinical consequences in women.

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页码：1699 / 1701

页数：3

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