Expression of engineered antibodies in plants: A possible tool for spiroplasma and phytoplasma disease control

被引：23

作者：

Chen, YD ^{[1
]}

Chen, TA ^{[1
]}

机构：

[1] Rutgers State Univ, Dept Plant Pathol, New Brunswick, NJ 08903 USA

来源：

PHYTOPATHOLOGY | 1998年 / 88卷 / 12期

关键词：

D O I：

10.1094/PHYTO.1998.88.12.1367

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In an attempt to develop maize plants with resistance to corn stunt spiroplasma (CSS), a single-chain Fv fragment (scFv) gene that was constructed from antibodies with strong inhibitory activity against CSS, was expressed in a cell line of maize. However, plants regenerated from this transgenic cell line showed no distinct resistance to CSS infection under the greenhouse conditions. The affinity and functionality of scFv in vivo and the locations of CSS and expressed scFv in maize could be a part of the contributing factors affecting this result. Progress of expressing antibodies in plants for plant pathogen resistance is also discussed.

引用

页码：1367 / 1371

页数：5

共 46 条

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