REST: A Toolkit for Resting-State Functional Magnetic Resonance Imaging Data Processing

被引：1686

作者：

Song, Xiao-Wei ^{[1
,2
]}

Dong, Zhang-Ye ^{[1
]}

Long, Xiang-Yu ^{[1
]}

Li, Su-Fang ^{[1
]}

Zuo, Xi-Nian ^{[3
]}

Zhu, Chao-Zhe ^{[1
]}

He, Yong ^{[1
]}

Yan, Chao-Gan ^{[1
]}

Zang, Yu-Feng ^{[1
,4
,5
]}

机构：

[1] Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China

[2] Chinese Acad Sci, Inst Biophys, Beijing 100080, Peoples R China

[3] Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China

[4] Hangzhou Normal Univ, Ctr Cognit & Brain Disorders, Hangzhou, Zhejiang, Peoples R China

[5] Hangzhou Normal Univ, Affiliated Hosp, Hangzhou, Zhejiang, Peoples R China

来源：

PLOS ONE | 2011年 / 6卷 / 09期

关键词：

INDEPENDENT COMPONENT ANALYSIS; ABNORMAL NEURAL ACTIVITY; DEFAULT-MODE NETWORK; REGIONAL HOMOGENEITY; BRAIN-FUNCTION; ALZHEIMERS-DISEASE; SIGNAL SOURCES; GLOBAL SIGNAL; FMRI SIGNAL; MRI;

D O I：

10.1371/journal.pone.0025031

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Resting-state fMRI (RS-fMRI) has been drawing more and more attention in recent years. However, a publicly available, systematically integrated and easy-to-use tool for RS-fMRI data processing is still lacking. We developed a toolkit for the analysis of RS-fMRI data, namely the RESting-state fMRI data analysis Toolkit (REST). REST was developed in MATLAB with graphical user interface (GUI). After data preprocessing with SPM or AFNI, a few analytic methods can be performed in REST, including functional connectivity analysis based on linear correlation, regional homogeneity, amplitude of low frequency fluctuation (ALFF), and fractional ALFF. A few additional functions were implemented in REST, including a DICOM sorter, linear trend removal, bandpass filtering, time course extraction, regression of covariates, image calculator, statistical analysis, and slice viewer (for result visualization, multiple comparison correction, etc.). REST is an open-source package and is freely available at http://www.restfmri.net.

引用

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