The design and performance of a simultaneous transmission and emission tomography system

被引:29
作者
Gullberg, GT [1 ]
Morgan, HT
Zeng, GSL
Christian, PE
Di Bella, EVR
Tung, CH
Maniawski, PJ
Hsieh, YL
Datz, FL
机构
[1] Univ Utah, Dept Radiol, Salt Lake City, UT 84132 USA
[2] Picker Int Inc, Cleveland, OH 44143 USA
关键词
Anger gamma camera; attenuation correction; brain SPECT; cardiac SPECT; clinical imaging hardware; clinical imaging software; emission computed tomography; fan-beam tomography; iterative reconstruction; simultaneous transmission and emission imaging; single-photon emission computed tomography; SPECT; transmission computed tomography;
D O I
10.1109/23.685291
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A commercial three-detector single-photon emission computed tomography (SPECT) system that enables simultaneous acquisition of transmission and emission data without increasing patient scanning time has been designed and manufactured. This system produces a reconstructed attenuation coefficient distribution that can be used to correct for photon attenuation in the emission reconstruction. The three detectors with fan-beam collimators are mounted to the gantry in a triangular arrangement. A transmission line source assembly was mounted at the focal line of one of the detectors and controlled to move in synchrony with the opposing fan-beam collimator, Data from transmission and emission sources at different energies were acquired in one detector, while the other two simultaneously acquired emission data. A transmission source of Gd-153 was used with Tc-99m-labeled radiopharmaceuticals, and Co-57 was used with Tl-201. Algorithms were developed to subtract crosstalk between transmission and emission energy windows in ail three detectors. A transmission maximum-likelihood iterative algorithm was used to reconstruct the attenuation distribution, which was used in combination with an iterative maximum-likelihood expectation-maximization algorithm to compensate for the attenuation of the projection of the emission distribution, The results in phantom studies displayed greater uniformity of activity with attenuation-corrected reconstruction. This was demonstrated visually and quantitatively by using anterior-to-inferior ratios close to one and low spatial %rms error as a measure of improved uniformity.
引用
收藏
页码:1676 / 1698
页数:23
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