Synthesis, structure and antifungal properties of Co(II)-sulfathiazolate complexes

被引：39

作者：

Bellú, S

Hure, E

Trapé, M

Trossero, C

Molina, G

Drogo, C

Williams, PAM

Atria, AM

Acevedo, JCM

Zacchino, S

Sortino, M

Campagnoli, D

Rizzotto, M

机构：

[1] Area Quim Inorgan, RA-2000 Rosario, Argentina

[2] UNLP, Fac Ciencias Exactas, CEQUINOR, La Plata, Argentina

[3] Univ Chile, Fac Ciencias Quim & Farmaceut, Santiago, Chile

[4] Univ Nacl Rosario, Area Farmacognosia, RA-2000 Rosario, Santa Fe, Argentina

[5] UNL, Fac Ingn Quim, RA-28293000 Santiago Del Estero, Santa Fe, Argentina

来源：

POLYHEDRON | 2005年 / 24卷 / 04期

关键词：

sulfathiazole; sulfadrugs metal complexes; cobalt complexes; antifungal properties;

D O I：

10.1016/j.poly.2004.12.017

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The reaction between sulfathiazole and cobalt(II) leads to a pink solid, [Co-II(ST)(2)(H2O)(4)] (1), which, after 7-10 days in the mother solution, transforms into red crystals of [Co-II(ST)(2)(H2O)(3)](n) (2) (ST = sulfathiazolate). The Co(II) ion exhibits an octahedral environment in both compounds. Differences between them were noted in the IR spectra in the region corresponding to signals of the amine group. Antifungal properties of (1) were evaluated, showing activity against both Aspergillus fumigatus (the same as the ligand) and Aspergillus flavus (better than the ligand). (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：501 / 509

页数：9

共 61 条

[1] Spectroscopic and saturation magnetization properties of the manganese- and cobalt-substituted Fur (ferric uptake regulation) protein from Escherichia coli [J].