The interaction between mercury(II) and sulfathiazole

被引:43
作者
Bellú, S
Hure, E
Trapé, M
Rizzotto, M
Sutich, E
Sigrist, M
Moreno, V
机构
[1] Univ Nacl Rosario, Area Quim Inorgan, RA-2000 Rosario, Santa Fe, Argentina
[2] Univ Nacl Rosario, Dept Microbiol, RA-2000 Rosario, Santa Fe, Argentina
[3] Univ Nacl Litoral, Fac Ingn Quim, RA-3000 Santa Fe, Argentina
[4] Univ Barcelona, Dept Quim Inorgan, E-08028 Barcelona, Spain
来源
QUIMICA NOVA | 2003年 / 26卷 / 02期
关键词
mercury complexes; sulfonamides; sulfonamide metal complexes;
D O I
10.1590/S0100-40422003000200008
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The interaction of mercury(II) with sulfathiazole has been analyzed. IR and NMR spectral studies suggest a coordination of Hg(II) with the N-thiazolic atom, unlike related Hg-sulfadrugs compounds. The complex was screened for its activity against Escherichia coli, showing an appreciable antimicrobial activity compared with the ligand.
引用
收藏
页码:188 / 192
页数:5
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