The interaction between mercury(II) and sulfathiazole

被引：43

作者：

Bellú, S

Hure, E

Trapé, M

Rizzotto, M

Sutich, E

Sigrist, M

Moreno, V

机构：

[1] Univ Nacl Rosario, Area Quim Inorgan, RA-2000 Rosario, Santa Fe, Argentina

[2] Univ Nacl Rosario, Dept Microbiol, RA-2000 Rosario, Santa Fe, Argentina

[3] Univ Nacl Litoral, Fac Ingn Quim, RA-3000 Santa Fe, Argentina

[4] Univ Barcelona, Dept Quim Inorgan, E-08028 Barcelona, Spain

来源：

QUIMICA NOVA | 2003年 / 26卷 / 02期

关键词：

mercury complexes; sulfonamides; sulfonamide metal complexes;

D O I：

10.1590/S0100-40422003000200008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The interaction of mercury(II) with sulfathiazole has been analyzed. IR and NMR spectral studies suggest a coordination of Hg(II) with the N-thiazolic atom, unlike related Hg-sulfadrugs compounds. The complex was screened for its activity against Escherichia coli, showing an appreciable antimicrobial activity compared with the ligand.

引用

页码：188 / 192

页数：5

共 27 条

[11] COMPLEX-FORMATION EQUILIBRIA BETWEEN THE ACETAZOLAMIDE ((5-ACETAMIDO-1,3,4-THIADIAZOLE)-2-SULFONAMIDE), A POTENT INHIBITOR OF CARBONICANHYDRASE, AND ZN(II), CO(II), NI(II) AND CU(II) IN AQUEOUS AND ETHANOL-AQUEOUS SOLUTIONS [J].