Evaluation of Therapeutic Targets in Animal Models of Arthritis How Does It Relate to Rheumatoid Arthritis?

被引:211
作者
Bevaart, Lisette [2 ]
Vervoordeldonk, Margriet J. [2 ]
Tak, Paul P. [1 ]
机构
[1] Univ Amsterdam, Div Clin Immunol & Rheumatol, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
[2] Arthrogen BV, Amsterdam, Netherlands
来源
ARTHRITIS AND RHEUMATISM | 2010年 / 62卷 / 08期
关键词
COLLAGEN-INDUCED ARTHRITIS; TUMOR-NECROSIS-FACTOR; WALL-INDUCED ARTHRITIS; INTERLEUKIN-1 RECEPTOR ANTAGONIST; PROTEOGLYCAN-INDUCED ARTHRITIS; ANTIBODY-INDUCED ARTHRITIS; AMELIORATES JOINT DISEASE; T-CELL-ACTIVATION; FLARE-UP REACTION; II COLLAGEN;
D O I
10.1002/art.27503
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:2192 / 2205
页数:14
相关论文
共 125 条
[1]   Functional analysis of an arthritogenic synovial fibroblast [J].
Aidinis, V ;
Plows, D ;
Haralambous, S ;
Armaka, M ;
Papadopoulos, P ;
Kanaki, MZ ;
Koczan, D ;
Thiesen, HJ ;
Kollias, G .
ARTHRITIS RESEARCH & THERAPY, 2003, 5 (03) :R140-R157
[2]   The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis [J].
Alten, Rieke ;
Gram, Hermann ;
Joosten, Leo A. ;
van den Berg, Wim B. ;
Sieper, Joachim ;
Wassenberg, Siegfrid ;
Burmester, Gerd ;
van Riel, Piet ;
Diaz-Lorente, Maria ;
Bruin, Gerardus Jm ;
Woodworth, Thasia G. ;
Rordorf, Christiane ;
Batard, Yannik ;
Wright, Andrew M. ;
Jung, Thomas .
ARTHRITIS RESEARCH & THERAPY, 2008, 10 (03)
[3]   INTERLEUKIN-1 RECEPTOR ANTAGONIST [J].
AREND, WP .
ADVANCES IN IMMUNOLOGY, VOL 54, 1993, 54 :167-227
[4]   Animal models of rheumatoid arthritis [J].
Asquith, Darren L. ;
Miller, Ashley M. ;
McInnes, Iain B. ;
Liew, Foo Y. .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2009, 39 (08) :2040-2044
[5]   Targeting nanomedicines in the treatment of rheumatoid arthritis: focus on certolizumab pegol [J].
Barnes, Theresa ;
Moots, Robert .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2007, 2 (01) :3-7
[6]  
Bendele A, 1999, ARTHRITIS RHEUM, V42, P498, DOI 10.1002/1529-0131(199904)42:3<498::AID-ANR15>3.0.CO
[7]  
2-A
[8]   Animal models of arthritis: Relevance to human disease [J].
Bendele, A ;
McComb, J ;
Gould, T ;
McAbee, T ;
Sennello, G ;
Chlipala, E ;
Guy, M .
TOXICOLOGIC PATHOLOGY, 1999, 27 (01) :134-142
[9]  
Bendele AM, 1999, CLIN EXP RHEUMATOL, V17, P553
[10]  
Bendele AM, 2000, ARTHRITIS RHEUM-US, V43, P2648, DOI 10.1002/1529-0131(200012)43:12<2648::AID-ANR4>3.0.CO