Validity and reliability of the CERAD-Col neuropsychological battery

被引：80

作者：

Aguirre-Acevedo, D. C. ^{[1
]}

Gomez, R. D. ^{[3
]}

Moreno, S. ^{[1
]}

Henao-Arboleda, E. ^{[1
]}

Motta, M. ^{[1
]}

Munoz, C. ^{[1
]}

Arana, A. ^{[2
]}

Pineda, D. A. ^{[1
,4
]}

Lopera, F. ^{[1
]}

机构：

[1] Univ Antioquia, Fac Med, Neurosci Grp, Medellin, Colombia

[2] Univ Antioquia, Fac Med, Serv Neurol, Medellin, Colombia

[3] Univ Antioquia, Fac Nacl Salud Publ, Medellin, Colombia

[4] Univ San Buenaventura, Grp Neuropsicol & Conduct, Medellin, Colombia

来源：

REVISTA DE NEUROLOGIA | 2007年 / 45卷 / 11期

关键词：

Alzheimer's disease; CERAD; dementia; neuropsychological; reliability; validity;

D O I：

10.33588/rn.4511.2007086

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction. Alzheimer's disease (AD) is an iniportant public health problem due to its disabling character and high individual, familial and social costs. The CERAD neuropsychological battery has been widely used for evaluation and diagnosis of the cognitive deficit associated with AD. This instrument has been adapted to the Colombian culture (CERAD-Col),for the Neurosciences Group. Subjects and methods. A study was carried out to establish the validity and reliability of the CERAD-Col in Colombian, Span ish-speaking individuals aged 50 years or more. It included 151 controls and 151 AD patients. Controls were selected from a convenience sample of 848 adults aged 50 years or more. The construct validity was determined in three ways:1) factorial analysis; 2) correlation with the functional scales FAST and GDS (convergent-type validity) and, 3) comparison between the two groups. Internal consistency was determined by means of Cronbach's alpha coefficient. Results. Three factors -memory, language and praxis- explained 88% of the total variance. Moderate but statistically significant correlations were found between neuropsychological tests and functional scales. Internal consistency and test-retest reproducibility were high. The AD group exhibited significantly lower scores (p < 0.05) than the control one. Conclusion. CERAD-Col is valid and reliable for the diagnosis of AD in Colombian Spanish-speaking population aged 50 years or more.

引用

页码：655 / 660

页数：6

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