Advances in the Negishi coupling

被引：19

作者：

Lessene, G ^{[1
]}

机构：

[1] Walter & Eliza Hall Inst Med Res, Struct Biol Div, Med Chem Grp, Bundoora, Vic 3086, Australia

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2004年 / 57卷 / 01期

关键词：

D O I：

10.1071/CH03225

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Palladium-catalyzed coupling reactions became part of a common set of reactions that chemists have to generate complex molecules. A particularly interesting version of this general reaction was the Negishi coupling. The discovery that zinc-derived reagents readily take part in palladium coupling reactions have provided a very mild and extremely efficient way to create carbon-carbon bonds from highly functionalized precursors.

引用

页码：107 / 107

页数：1

共 10 条

[1]

Boudier A, 2000, ANGEW CHEM INT EDIT, V39, P4414, DOI 10.1002/1521-3773(20001215)39:24<4414::AID-ANIE4414>3.0.CO

[2]

2-C

[3] The first general method for palladium-catalyzed Negishi cross-coupling of aryl and vinyl chlorides:: Use of commercially available Pd(P(t-BU)3)2 as a catalyst [J].

Dai, CY ;

Fu, GC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (12) :2719-2724

[4] Diazonamide synthesis studies: Use of Negishi coupling to fashion diazonamide-related biaryls with defined axial chirality [J].

Feldman, KS ;

Eastman, KJ ;

Lessene, G .

ORGANIC LETTERS, 2002, 4 (20) :3525-3528

[5] Ni(II)-catalyzed cross-coupling between polyfunctional arylzinc derivatives and primary alkyl iodides [J].

Giovannini, R ;

Knochel, P .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (43) :11186-11187

[6] Highly efficient, general procedure for the preparation of alkylzinc reagents from unactivated alkyl bromides and chlorides [J].

Huo, SQ .

ORGANIC LETTERS, 2003, 5 (04) :423-425

[7] PREPARATION OF NEW CLASSES OF ALIPHATIC, ALLYLIC, AND BENZYLIC ZINC AND COPPER REAGENTS BY THE INSERTION OF ZINC DUST INTO ORGANIC HALIDES, PHOSPHATES, AND SULFONATES [J].

JUBERT, C ;

KNOCHEL, P .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (20) :5425-5431

[8] PREPARATION AND REACTIONS OF POLYFUNCTIONAL ORGANOZINC REAGENTS IN ORGANIC-SYNTHESIS [J].

KNOCHEL, P ;

SINGER, RD .

CHEMICAL REVIEWS, 1993, 93 (06) :2117-2188

[9]

Negishi E, 1998, METAL-CATALYZED CROSS-COUPLING REACTIONS, P1

[10] Air-stable trialkylphosphonium salts: Simple, practical, and versatile replacements for air-sensitive trialkylphosphines. Applications in stoichiometric and catalytic processes [J].

Netherton, MR ;

Fu, GC .

ORGANIC LETTERS, 2001, 3 (26) :4295-4298

← 1 →