The endocannabinoid system in vertebrate male reproduction: A comparative overview

被引：39

作者：

Cacciola, Giovanna ^{[1
]}

Chioccarelli, Teresa ^{[1
]}

Ricci, Giulia ^{[2
]}

Meccariello, Rosaria ^{[3
]}

Fasano, Silvia ^{[1
]}

Pierantoni, Riccardo ^{[1
]}

Cobellis, Gilda ^{[1
]}

机构：

[1] Univ Naples 2, Dipartimento Med Sperimentale, Sez F Bottazzi, I-80138 Naples, Italy

[2] Univ Naples 2, Dipartimento Med Sperimentale, Sez F Bottazzi, Lab Istol, I-80138 Naples, Italy

[3] Univ Napoli Parthenope, Dipartimento Studi Ist & Sistemi Territoriali, I-80133 Naples, Italy

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2008年 / 286卷 / 1-2期

关键词：

endocannabinoids; cannabinoids; male reproductive tract; cannabinoid receptors;

D O I：

10.1016/j.mce.2008.01.004

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Prevailing studies emphasize on endocannabinoid activity in brain. However, sporadic evidences hint that endocannabinoid system controls male reproduction ranging from invertebrates to vertebrates. Although N-arachidonoylethanolamine is described in rat testis, its activity is still poorly known. Type-1 cannabinoid receptor and fatty acid amide hydrolase are particularly expressed in elongating spermatids and spermatozoa suggesting that endocannabinoids affect spermiogenesis and sperm physiology. Aim of this paper is to provide an analysis of the information available in vertebrates on male germ cell progression and sperm maturation mediated by the endocannabinoid system. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S24 / S30

页数：7

共 64 条

[41] Estrogen and spermatogenesis [J].

O'Donnell, L ;

Robertson, KM ;

Jones, ME ;

Simpson, ER .

ENDOCRINE REVIEWS, 2001, 22 (03) :289-318

[42] Molecular characterization of a phospholipase D generating anandamide and its congeners [J].

Okamoto, Y ;

Morishita, J ;

Tsuboi, K ;

Tonai, T ;

Ueda, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (07) :5298-5305

[43] Cannabinoid receptors and their ligands [J].

Pertwee, RG ;

Ross, RA .

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2002, 66 (2-3) :101-121

[44] (-)-cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens [J].

Pertwee, RG ;

Ross, RA ;

Craib, SJ ;

Thomas, A .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2002, 456 (1-3) :99-106

[45] The amphibian testis as model to study germ cell progression during spermatogenesis [J].

Pierantoni, R ;

Cobellis, G ;

Meccariello, R ;

Palmiero, C ;

Fienga, G ;

Minucci, S ;

Fasano, S .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2002, 132 (01) :131-139

[46]

Pierantoni R, 2002, INT REV CYTOL, V218, P69

[47]

PIERANTONI R, 1999, FUNCTIONAL MORPHOLOG, P225

[48]

PIERANTONI R, 1998, ENCY REPROD, V3, P10

[49] Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor [J].

Porter, AC ;

Sauer, JM ;

Knierman, MD ;

Becker, GW ;

Berna, MJ ;

Bao, JQ ;

Nomikos, GG ;

Carter, P ;

Bymaster, FP ;

Leese, AB ;

Felder, CC .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 301 (03) :1020-1024

[50]

PRATT HL, 1998, COPEIA, V3, P719

← 1 2 3 4 5 6 7 →