Estrogens in vascular biology and disease:: where do we stand today?

被引：60

作者：

Arnal, Jean-Francois

Scarabin, Pierre-Yves

Tremollieres, Florence

Laurell, Henrik

Gourdy, Pierre

机构：

[1] CHU Toulouse Rangueil, Dept Vasc Biol & Atherothrombosis, INSERM, U858,12MR, F-31432 Toulouse 4, France

[2] Hop Paul Brousse, Cardiovasc Epidemiol Team, Villejuif, France

来源：

CURRENT OPINION IN LIPIDOLOGY | 2007年 / 18卷 / 05期

关键词：

atheroma; atherosclerosis; cardiovascular risk; oestrogens; thrombosis;

D O I：

10.1097/MOL.0b013e3282ef3bca

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A better understanding of the balance between the deleterious and beneficial effects of estrogens is required and should help to improve hormonal therapy safety and to optimize the prevention of cardiovascular disease after menopause.

引用

页码：554 / 560

页数：7

共 71 条

[21] Identification of a new isoform of the human estrogen receptor-alpha (hER-α) that is encoded by distinct transcripts and that is able to repress hER-α activation function 1 [J].

Flouriot, G ;

Brand, H ;

Denger, S ;

Metivier, R ;

Kos, M ;

Reid, G ;

Sonntag-Buck, V ;

Gannon, F .

EMBO JOURNAL, 2000, 19 (17) :4688-4700

[22] 17β-estradiol inhibits inflammatory gene expression by controlling NF-κB intracellular localization [J].

Ghisletti, S ;

Meda, C ;

Maggi, A ;

Vegeto, E .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (08) :2957-2968

[23] Relevance of sexual dimorphism to regulatory T cells:: estradiol promotes IFN-γ production by invariant natural killer T cells [J].

Gourdy, P ;

Araujo, LM ;

Zhu, R ;

Garmy-Susini, B ;

Diem, S ;

Laurell, H ;

Leite-de-Moraes, M ;

Dy, M ;

Amal, JF ;

Bayard, F ;

Herbelin, A .

BLOOD, 2005, 105 (06) :2415-2420

[24] Postmenopausal hormones - Therapy for symptoms only [J].

Grady, D .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (19) :1835-1837

[25] Postmenopausal estrogen and progestin use and the risk of cardiovascular disease [J].

Grodstein, F ;

Stampfer, MJ ;

Manson, JE ;

Colditz, GA ;

Willett, WC ;

Rosner, B ;

Speizer, FE ;

Hennekens, CH .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (07) :453-461

[26] ESTROGEN MONOTHERAPY AND COMBINED ESTROGEN-PROGESTOGEN REPLACEMENT THERAPY ATTENUATE AORTIC ACCUMULATION OF CHOLESTEROL IN OVARIECTOMIZED CHOLESTEROL-FED RABBITS [J].

HAARBO, J ;

LETHESPENSEN, P ;

STENDER, S ;

CHRISTIANSEN, C .

JOURNAL OF CLINICAL INVESTIGATION, 1991, 87 (04) :1274-1279

[27] The immune response in atherosclerosis: a double-edged sword [J].

Hansson, Goran K. ;

Libby, Peter .

NATURE REVIEWS IMMUNOLOGY, 2006, 6 (07) :508-519

[28] Effects of estrogen plus progestin on health-related quality of life [J].

Hays, J ;

Ockene, JK ;

Brunner, RL ;

Kotchen, JM ;

Manson, JE ;

Patterson, RE ;

Aragaki, AK ;

Shumaker, SA ;

Brzyski, RG ;

LaCroix, AZ ;

Granek, IA ;

Valanis, BG .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (19) :1839-1854

[29] Minireview: Estrogen and mouse models of atherosclerosis [J].

Hodgin, JB ;

Maeda, N .

ENDOCRINOLOGY, 2002, 143 (12) :4495-4501

[30] Estrogen receptor α is a major mediator of 17β-estradiol's atheroprotective effects on lesion size in Apoe-/- mice [J].

Hodgin, JB ;

Krege, JH ;

Reddick, RL ;

Korach, KS ;

Smithies, O ;

Maeda, N .

JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (03) :333-340

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