Nano-Hydroxyapatite/Polymer Composite as Bone Repair Materials

被引:15
作者
Liao Jianguo [1 ]
Li Yanqun [1 ]
Duan Xingze [1 ]
Zhu Lingli [1 ]
机构
[1] Henan Polytech Univ, Sch Mat Sci & Engn, Cultivating Base Key Lab Environm Friendly Inorga, Jiaozuo 454000, Peoples R China
基金
中国国家自然科学基金;
关键词
nano-hydroxyapatite; bone repair; polymers; composites; IN-VIVO EVALUATION; MECHANICAL-PROPERTIES; POLYETHYLENE COMPOSITES; TISSUE REPLACEMENT; SILK FIBROIN; COLLAGEN; SCAFFOLDS; CHITOSAN; BIOMATERIALS; APATITE;
D O I
10.7536/PC140810
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The searching of ideal bone repair materials has always been one of research hot spots in the field of orthopedics. Natural bones are nanocomposites mainly composed of nano-hydroxyapatite and collagen. Nano-hydroxyapatite/polymer composites, derived from imitation of natural hard tissue, combine polymer matrix with high toughness and nano-hydroxyapatite crystals with high rigidity. These nanocomposites have high toughness since they maximize the complementary advantages. Structure factors are equally important to composition for the high performance of these composites, which include architectural organization and controlled orientation in different dimensions. Nano-hydroxyapatite/polymer composite materials have become a research hot spot and development direction in the field of bone tissue repair materials. This paper summarizes the research progress and status in the aspects of preparation and properties of these materials used for the repair of body hard tissue, and predicts its future development.
引用
收藏
页码:220 / 228
页数:9
相关论文
共 62 条
[31]   Osteoblasts adherence and migration through three-dimensional porous mineralized collagen based composite: nHAC/PLA [J].
Liao, SS ;
Cui, FZ ;
Zhu, Y .
JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 2004, 19 (02) :117-130
[32]   Hierarchically biomimetic bone scaffold materials: Nano-HA/collagen/PLA composite [J].
Liao, SS ;
Cui, FZ ;
Zhang, W ;
Feng, QL .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2004, 69B (02) :158-165
[33]   Mechanics of collagen-hydroxyapatite model nanocomposites [J].
Libonati, Flavia ;
Nair, Arun K. ;
Vergani, Laura ;
Buehler, Markus J. .
MECHANICS RESEARCH COMMUNICATIONS, 2014, 58 :17-23
[34]   High density polyethylene/ultra high molecular weight polyethylene blend. II. Effect of hydroxyapatite on processing, thermal, and mechanical properties [J].
Lim, KLK ;
Ishak, ZAM ;
Ishiaku, US ;
Fuad, AMY ;
Yusof, AH ;
Czigany, T ;
Pukanzsky, B ;
Ogunniyi, DS .
JOURNAL OF APPLIED POLYMER SCIENCE, 2006, 100 (05) :3931-3942
[35]  
Lin Xiao-Yan, 2006, Chinese Journal of Biomedical Engineering, V25, P63
[36]  
Lu GY, 2006, TSINGHUA SCI TECHNOL, V11, P427
[37]   Supercritical assisted atomization to produce nanostructured chitosan-hydroxyapatite microparticles for biomedical application [J].
Reverchon, Ernesto ;
Adami, Renata .
POWDER TECHNOLOGY, 2013, 246 :441-447
[38]   Biomimetic configurational arrays of hydroxyapatite nanocrystals on bio-organics [J].
Rhee, SH ;
Suetsugu, Y ;
Tanaka, J .
BIOMATERIALS, 2001, 22 (21) :2843-2847
[39]   Processing and mechanical properties of hydroxyapatite-polysulfone laminated composites [J].
Robinson, P., II ;
Wilson, C., II ;
Mecholsky, J., Jr. .
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2014, 34 (05) :1387-1396
[40]   Exploring and engineering the cell surface interface [J].
Stevens, MM ;
George, JH .
SCIENCE, 2005, 310 (5751) :1135-1138