AIDS: A role for host genes

被引：17

作者：

O'Brien, SJ ^{[1
]}

机构：

[1] NCI, Lab Genom Divers, Frederick, MD 21701 USA

来源：

HOSPITAL PRACTICE | 1998年 / 33卷 / 07期

关键词：

D O I：

10.3810/hp.1998.07.96

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Suspicion that human genes affect the natural history of AIDS has been confirmed by discoveries of three such genes, one of which confers near-total immunity in about 1% of Caucasians. The findings suggest a novel therapeutic target: not HIV but the hosts cooperation with it. They also herald an era in which genomes are seen as having been shaped by the evolutionary pressures of infection, and may thus hold evolution-tested therapies.

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页码：53 / +

页数：14

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