Mean Platelet Volume: A New Predictor in Confirming Acute Appendicitis Diagnosis

被引：102

作者：

Albayrak, Yavuz ^{[1
,2
]}

Albayrak, Ayse ^{[3
]}

Albayrak, Fatih ^{[4
]}

Yildirim, Rahsan ^{[4
]}

Aylu, Belkiz ^{[1
]}

Uyanik, Abdullah ^{[4
]}

Kabalar, Esref ^{[5
]}

Guzel, Ibrahim C. ^{[5
]}

机构：

[1] Erzurum Reg Educ & Res Hosp, Dept Gen Surg, Erzurum, Turkey

[2] Erzurum Reg Educ & Res Hosp, Burn Unit, Erzurum, Turkey

[3] Erzurum Reg Educ & Res Hosp, Dept Clin Bacteriol & Infect Dis, Erzurum, Turkey

[4] Ataturk Univ, Sch Med, Dept Internal Med, Erzurum, Turkey

[5] Erzurum Reg Educ & Res Hosp, Dept Pathol, Erzurum, Turkey

来源：

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | 2011年 / 17卷 / 04期

关键词：

acute appendicitis; mean platelet volume; complete blood count; positive predictive value; BLOOD-CELL COUNT; ULCERATIVE-COLITIS; DISEASE; MARKER;

D O I：

10.1177/1076029610364520

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: The purpose of this study was to investigate the diagnostic value of mean platelet volume (MPV) in acute appendicitis (AA). Methods: Our study was carried out in 206 healthy control groups and 226 patients who had a preliminary diagnosis of AA. Results: A statistically significant decrease in MPV was noted in patients with AA compared with healthy controls (P < .001). The best MPV level cutoff point for AA was 7.6 fL, with a sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 73%, 84%, 84%, and 74%, respectively. Conclusions: As the MPV value is included in the complete blood count (CBC) analysis, it increases the sensitivity and NPVs of white blood cell (WBC) in AA diagnosis without the need for extra analyses, loss of time, or cost increase. Therefore, we believe that the MPV value should also be taken into consideration along with the WBC in every patient with suspected AA.

引用

页码：362 / 366

页数：5

共 21 条

[1] The appendicitis inflammatory response score: A tool for the diagnosis of acute appendicitis that outperforms the Alvarado score [J].

Andersson, Manne ;

Andersson, Roland E. .

WORLD JOURNAL OF SURGERY, 2008, 32 (08) :1843-1849

[2]

ANDERSSON RE, 1992, EUR J SURG, V158, P37

[3]

Bansal R, 2002, J Indian Acad Clin Med, V3, P169

[4] Platelet size: Measurement, physiology and vascular disease [J].

Bath, PMW ;

Butterworth, RJ .

BLOOD COAGULATION & FIBRINOLYSIS, 1996, 7 (02) :157-161

[5] Mean platelet volume in neonatal respiratory distress syndrome [J].

Canpolat, Fuat Emre ;

Yurdakoek, Murat ;

Armangil, Didem ;

Yigit, Sule .

PEDIATRICS INTERNATIONAL, 2009, 51 (02) :314-316

[6]

Cardall T, 2004, ACAD EMERG MED, V11, P1021, DOI [10.1111/j.1553-2712.2004.tb00670.x, 10.1197/j.aem.2004.004.011]

[7] The mean platelet volume in subjects with impaired fasting glucose [J].

Coban, E ;

Bostan, F ;

Ozdogan, M .

PLATELETS, 2006, 17 (01) :67-69

[8] Platelets in inflammatory bowel disease: Clinical, pathogenic, and therapeutic implications [J].

Danese, S ;

de la Motte, C ;

Fiocchi, C .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (05) :938-945

[9] Serum interleukin-6 measurement in the diagnosis of acute appendicitis [J].

Gürleyik, G ;

Gürleyik, E ;

Çetinkaya, F ;

Unalmiser, S .

ANZ JOURNAL OF SURGERY, 2002, 72 (09) :665-667

[10] Reticulated platelet levels in patients with ulcerative colitis [J].

Kayahan, Hasan ;

Akarsu, Mesut ;

Ozcan, Mehmet Ali ;

Demir, Serdal ;

Ates, Halil ;

Unsal, Belkis ;

Akpinar, Hale .

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2007, 22 (12) :1429-1435

← 1 2 3 →