Mean Platelet Volume: A New Predictor in Confirming Acute Appendicitis Diagnosis

被引:102
作者
Albayrak, Yavuz [1 ,2 ]
Albayrak, Ayse [3 ]
Albayrak, Fatih [4 ]
Yildirim, Rahsan [4 ]
Aylu, Belkiz [1 ]
Uyanik, Abdullah [4 ]
Kabalar, Esref [5 ]
Guzel, Ibrahim C. [5 ]
机构
[1] Erzurum Reg Educ & Res Hosp, Dept Gen Surg, Erzurum, Turkey
[2] Erzurum Reg Educ & Res Hosp, Burn Unit, Erzurum, Turkey
[3] Erzurum Reg Educ & Res Hosp, Dept Clin Bacteriol & Infect Dis, Erzurum, Turkey
[4] Ataturk Univ, Sch Med, Dept Internal Med, Erzurum, Turkey
[5] Erzurum Reg Educ & Res Hosp, Dept Pathol, Erzurum, Turkey
关键词
acute appendicitis; mean platelet volume; complete blood count; positive predictive value; BLOOD-CELL COUNT; ULCERATIVE-COLITIS; DISEASE; MARKER;
D O I
10.1177/1076029610364520
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: The purpose of this study was to investigate the diagnostic value of mean platelet volume (MPV) in acute appendicitis (AA). Methods: Our study was carried out in 206 healthy control groups and 226 patients who had a preliminary diagnosis of AA. Results: A statistically significant decrease in MPV was noted in patients with AA compared with healthy controls (P < .001). The best MPV level cutoff point for AA was 7.6 fL, with a sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 73%, 84%, 84%, and 74%, respectively. Conclusions: As the MPV value is included in the complete blood count (CBC) analysis, it increases the sensitivity and NPVs of white blood cell (WBC) in AA diagnosis without the need for extra analyses, loss of time, or cost increase. Therefore, we believe that the MPV value should also be taken into consideration along with the WBC in every patient with suspected AA.
引用
收藏
页码:362 / 366
页数:5
相关论文
共 21 条
[11]  
Kiliçli-Çamur N, 2005, MED SCI MONITOR, V11, pCR387
[12]   Mean platelet volume (MPV) as an inflammatory marker in ankylosing spondylitis and rheumatoid arthritis [J].
Kisacik, Bunyamin ;
Tufan, Abdurrahman ;
Kalyoncu, Umut ;
Karadag, Omer ;
Akdogan, Ali ;
Ozturk, Mehmet Akif ;
Kiraz, Sedat ;
Ertenli, Ihsan ;
Calguneri, Meral .
JOINT BONE SPINE, 2008, 75 (03) :291-294
[13]   Mean platelet volume in children with familial Mediterranean fever [J].
Makay, Balahan ;
Turkyilmaz, Zeynep ;
Unsal, Erbil .
CLINICAL RHEUMATOLOGY, 2009, 28 (08) :975-978
[14]  
Sack Ulrich, 2006, BMC Surg, V6, P15
[15]  
Shafi Sheikh Muzamil, 2009, Saudi J Gastroenterol, V15, P117, DOI 10.4103/1319-3767.48969
[16]   Platelets as predictors of vascular risk: Is there a practical index of platelet activity? [J].
Tsiara, S ;
Elisaf, M ;
Jagroop, IA ;
Mikhailidis, DP .
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2003, 9 (03) :177-190
[17]   Effect of prolonged stay at high altitude on platelet aggregation and fibrinogen levels [J].
Vij, Anjana G. .
PLATELETS, 2009, 20 (06) :421-427
[18]   The use of white blood cell count and left shift in the diagnosis of appendicitis in children. [J].
Wang, Linda T. ;
Prentiss, Kimball A. ;
Simon, Jill Z. ;
Doody, Daniel P. ;
Ryan, Daniel P. .
PEDIATRIC EMERGENCY CARE, 2007, 23 (02) :69-76
[19]   Plateletcrit, mean platelet volume, platelet distribution width: Its expected values and correlation with parallel red blood cell parameters [J].
Wiwanitkit, V .
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2004, 10 (02) :175-178
[20]   Laboratory tests in patients with acute appendicitis [J].
Yang, HR ;
Wang, YC ;
Chung, PK ;
Chen, WK ;
Jeng, LB ;
Chen, RJ .
ANZ JOURNAL OF SURGERY, 2006, 76 (1-2) :71-74