Prevention of recurrent spontaneous abortion by intravenous immunoglobulin: a double-blind placebo-controlled study

被引：82

作者：

Jablonowska, B ^{[1
]}

Selbing, A

Palfi, M

Ernerudh, J

Kjellberg, S

Lindton, B

机构：

[1] Linkoping Univ Hosp, Dept Obstet & Gynecol, S-58185 Linkoping, Sweden

[2] Linkoping Univ Hosp, Dept Clin Immunol & Transfus Med, S-58185 Linkoping, Sweden

[3] Huddinge Univ Hosp, Dept Obstet & Gynecol, S-14186 Huddinge, Sweden

来源：

HUMAN REPRODUCTION | 1999年 / 14卷 / 03期

关键词：

intravenous immunoglobulin; recurrent spontaneous abortion;

D O I：

10.1093/humrep/14.3.838

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The aim of this study was to evaluate the therapeutic efficacy of intravenous immunoglobulin (IVIG) in the prevention of recurrent spontaneous abortion (RSA), In a double-blind, randomized, placebo-controlled study, 41 women with a history of unexplained recurrent spontaneous abortion were treated with IVIG or saline infusions during pregnancy. The birth of a child was considered a successful outcome. The overall success rate was 77% in the IVIG group compared with 79% in the placebo group. For women with primary RSA the success rates were 82 (IVIG) and 89% (placebo), and for women with secondary RSA the rates were 73 (IVIG) and 70% (placebo). We found no statistically significant difference in treatment results between IVIG and placebo.

引用

页码：838 / 841

页数：4

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