The performance of a scaled down industrial disc stack centrifuge with a reduced feed material requirement

被引:30
作者
Maybury, JP [1 ]
Mannweiler, K [1 ]
Titchener-Hooker, NJ [1 ]
Hoare, M [1 ]
Dunnill, P [1 ]
机构
[1] Univ London Univ Coll, Dept Chem & Biochem Engn, Adv Ctr Biochem Engn, London WC1E 7JE, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1007/s004490050430
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A method is described for the scale-down of a disc stack centrifuge which reduces the number of separating discs and also the liquid and solid hold-up of the centrifuge bowl. This is to enable a reduced volume of process material to be used for study of clarification. Scale-down is achieved in stages using a series of interlocking inserts to suit particular applications. Maximum scale-down gives a 76% reduction in the separation area and a bowl volume reduction of 70%. Separation performance of the full stack machine and scale-down variants is compared using the grade efficiency concept. Polyvinyl acetate and bakers' yeast homogenate particle suspensions are used for the comparison. The grade efficiency curves produced by the scale-down variants closely follow the curves for the full stack machine. This resulted in supernatants of the same volume size distribution and concentration when using scale-down methodology to mimic the full scale operation.
引用
收藏
页码:191 / 199
页数:9
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