On the metallation of 2-isopropylpyridine.

被引：47

作者：

Pasquinet, E ^{[1
]}

Rocca, P ^{[1
]}

Marsais, F ^{[1
]}

Godard, A ^{[1
]}

Quéguiner, G ^{[1
]}

机构：

[1] INSA Rouen, IRCOF, CNRS, UPRESA 6014, F-76131 Mont St Aignan, France

来源：

TETRAHEDRON | 1998年 / 54卷 / 30期

关键词：

deprotonation; metallation; potassium compounds; pyridine;

D O I：

10.1016/S0040-4020(98)00507-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Isopropylpyridine has been successfully metallated and functionalized by using potassium diisopropylamide (KDA). Subsequent functionalization has been achieved with a wide range of electrophiles and good to excellent yields have been obtained. The action of other potassium or sodium bases has also been investigated. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8771 / 8782

页数：12

共 54 条

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