Gene transfer in haematological malignancy

被引：6

作者：

Brenner, MK

机构：

[1] St. Jude Children's Research Hospital, Memphis, TN

[2] Cell and Gene Therapy Program, St. Jude Children's Research Hospital, Memphis, TN 38105-2794

来源：

ANNALS OF MEDICINE | 1996年 / 28卷 / 06期

关键词：

cytotoxic T cells; gene therapy; haematological malignancies; haematopoietic stem cells; vectors;

D O I：

10.3109/07853899608999113

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Although gene transfer was first suggested to treat inherited monogenic disorders, at present most clinical protocols are intended to treat patients with malignant disease. Although current vector technologies profoundly limit the potential therapeutic applications of gene transfer, the technique is already being successfully used to complement longer established therapies. This article reviews current and forthcoming applications of gene transfer to treat haematological malignancies.

引用

页码：491 / 497

页数：7

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