CD1 and lipid antigens: intracellular pathways for antigen presentation

被引：39

作者：

Jayawardena-Wolf, J ^{[1
]}

Bendelac, A ^{[1
]}

机构：

[1] Princeton Univ, Dept Mol Biol, Schultz Lab, Princeton, NJ 08544 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2001年 / 13卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0952-7915(00)00190-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recently, different members of the CD1 family of MHC-like molecules have been shown to sample different intracellular compartments to present lipid and glycolipid antigens to T cells. Emerging models suggest that CD1 may have evolved to monitor the integrity of membrane lipids and/or to present microbial lipid antigens to both alpha beta and gamma delta T cells.

引用

页码：109 / 113

页数：5

共 40 条

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