Analyzing sleep abnormalities in HIV-infected patients treated with efavirenz

被引：112

作者：

Gallego, L

Barreiro, P

del Río, R

de Requena, DG

Rodríguez-Albariño, A

González-Lahoz, J

Soriano, V

机构：

[1] Inst Salud Carlos III, Hosp Carlos III, Infect Dis Serv, Madrid, Spain

[2] Inst Salud Carlos III, Hosp Carlos III, Serv Pharm, Madrid, Spain

[3] Hosp La Paz, Serv Clin Neurophysiol, Madrid, Spain

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 38卷 / 03期

关键词：

D O I：

10.1086/380791

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ambulatory electroencephalogram monitoring was performed for 18 HIV-infected subjects treated with efavirenz with and without insomnia and for 13 healthy control subjects. All patients receiving efavirenz had longer sleep latencies and shorter duration of deep sleep, although poor sleepers also showed reduced sleep efficiency and shorter duration of rapid eye movement sleep. Efavirenz plasma levels were higher in patients with insomnia and/or reduced sleep efficiency.

引用

页码：430 / 432

页数：3

共 9 条

[1] Blanch J, 2001, J ACQ IMMUN DEF SYND, V27, P336, DOI 10.1097/00126334-200108010-00003
[2] THE PITTSBURGH SLEEP QUALITY INDEX - A NEW INSTRUMENT FOR PSYCHIATRIC PRACTICE AND RESEARCH
BUYSSE, DJ
REYNOLDS, CF
MONK, TH
BERMAN, SR
KUPFER, DJ
[J]. PSYCHIATRY RESEARCH, 1989, 28 (02) : 193 - 213
[3] Ambulatory EEG monitoring
Gilliam, F
Kuzniecky, R
Faught, E
[J]. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 1999, 16 (02) : 111 - 115
[4] HUMAN SLOW-WAVE SLEEP - A REVIEW AND APPRAISAL OF RECENT FINDINGS, WITH IMPLICATIONS FOR SLEEP FUNCTIONS, AND PSYCHIATRIC-ILLNESS
HORNE, J
[J]. EXPERIENTIA, 1992, 48 (10): : 941 - 954
[5] Validation of a simplified medication adherence questionnaire in a large cohort of HIV-infected patients:: the GEEMA Study
Knobel, H
Alonso, J
Casado, JL
Collazos, J
González, J
Ruiz, I
Kindelan, JM
Carmona, A
Juega, J
Ocampo, A
[J]. AIDS, 2002, 16 (04) : 605 - 613
[6] Núñez M, 2001, J ACQ IMMUN DEF SYND, V28, P399
[7] Effects of drugs on sleep
Obermeyer, WH
Benca, RM
[J]. NEUROLOGIC CLINICS, 1996, 14 (04) : 827 - &
[8] High prevalence of insomnia in an outpatient population with HIV infection
Rubinstein, ML
Selwyn, PA
[J]. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1998, 19 (03): : 260 - 265
[9] Drug-induced nightmares
Thompson, DF
Pierce, DR
[J]. ANNALS OF PHARMACOTHERAPY, 1999, 33 (01) : 93 - 98

← 1 →